勃雄二醇 |
臨床資料 |
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其他名稱 | 19-Norandrostenediol; 19-Nor-4-androstene-3β,17β-diol; Estr-4-ene-3β,17β-diol; 3β-Dihydronandrolone |
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识别信息 |
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(3S,8R,9S,10R,13S,14S,17S)-13-methyl-1,2,3,6,7,8,9,10,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol
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CAS号 | 19793-20-5 |
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PubChem CID | |
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ChemSpider | |
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ChEMBL | |
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CompTox Dashboard (EPA) | |
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化学信息 |
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化学式 | C18H28O2 |
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摩尔质量 | 276.42 g·mol−1 |
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3D模型(JSmol) | |
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O[C@@H]4/C=C2\[C@@H]([C@H]1CC[C@@]3([C@@H](O)CC[C@H]3[C@@H]1CC2)C)CC4
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InChI=1S/C18H28O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,12-17,19-20H,2-9H2,1H3/t12-,13-,14+,15+,16-,17-,18-/m0/s1 Key:CMXKUJNZWYTFJN-XFUVECHXSA-N
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勃雄二醇(英語:Bolandiol。INN,也被称为19-去甲-4-雄烯二醇,19-nor-4-androstenediol,雌甾-4-烯-3β,17β-二醇,estr-4-en-3β,17β-diol,或3β-双氢诺龙,3β-dihydronandrolone)是一种同化類固醇(AAS),从未上市[1]。其二丙酸酯——二丙酸勃雄二醇酯已上市[1][2]。勃雄二醇与其二丙酸酯除了具有AAS活性外,还具有一定的雌激素与孕激素活性[3][4]。
另见
参考文献
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| 受体 | |
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| 酶 (抑制剂) | | - 22-ABC
- 3,3′-Dimethoxybenzidine
- 3-Methoxybenzidine
- Aminoglutethimide
- Cyanoketone
- Danazol
- Etomidate
- Mitotane
- Trilostane
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| 3β-HSD (I, II) | |
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| 17β-HSD (I-XIV) | |
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| | - 22-Oxime
- Alfatradiol
- Azelaic acid
- β-Sitosterol
- Bexlosteride
- Dutasteride
- 表睾酮
- Epristeride
- Finasteride
- Izonsteride
- L-39
- Lapisteride
- Polyunsaturated fatty acids (α-linolenic acid, linoleic acid, γ-linolenic acid, oleic acid)
- Turosteride
- Vitamin B6
- 锌
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| | - 1,4,6-Androstatriene-3,17-dione
- 4-Androstene-3,6,17-trione
- 4-Cyclohexylaniline
- 4-Hydroxytestosterone
- 5α-DHNET
- Abyssinone II
- Aminoglutethimide
- Anastrozole
- 抗坏血酸(维生素C)
- Atamestane
- Bifonazole
- CGP-45,688
- CGS-47,645
- Clotrimazole
- 双氢睾酮
- Difeconazole
- Econazole
- Exemestane
- Fadrozole
- Fenarimol
- Finrozole
- Formestane
- Imazalil
- Isoconazole
- Ketoconazole
- Letrozole
- Liarozole
- MEN-11066
- Miconazole
- Minamestane
- Nimorazole
- NKS01
- ORG-33,201
- Penconazole
- Plomestane
- Prochloraz
- Propioconazole
- Pyridoglutethimide
- Rogletimide
- Rotenone
- Talarozole
- Testolactone
- Tioconazole
- Triadimefon
- Triadimenol
- Troglitazone
- Vorozole
- YM511
- 锌
Note: 21-Hydroxylase inhibitors may also affect androgen levels as they prevent metabolism of androgen steroid precursors. |
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| 其他 | | |
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| 间接 | - Estrogens/Antiestrogens (see here)
- GnRH agonists/antagonists (see here)
- Gonadotropins/Antigonadotropins (see here)
- Plasma proteins (SHBG, ABP, Albumin)
- Progestogens/Antiprogestins (see here)
- Prolactin
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