Flutrimazole

Flutrimazole
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	D01AC16 (WHO) G01AF18 (WHO);
Identifiers
	IUPAC name (RS)-1-[(2-Fluorophenyl)(4-fluorophenyl)benzyl]-1H-imidazole;
CAS Number	119006-77-8 ;
PubChem CID	3401;
ChemSpider	3284 ;
UNII	776S0UP252;
KEGG	D07193 ;
ChEBI	CHEBI:82864 ;
ChEMBL	ChEMBL2107430 ;
CompTox Dashboard (EPA)	DTXSID30869622 ;
ECHA InfoCard	100.170.770
Chemical and physical data
Formula	C22H16F2N2
Molar mass	346.381 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4;
	InChI InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H ; Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N ;
	(what is this?) (verify)

Flutrimazole is a wide-spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. Its antifungal activity has been demonstrated in in vivo and in vitro studies to be comparable to that of clotrimazole and higher than bifonazole.^[1]

Mechanism of action

It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol 14 α-demethylase.^{[citation needed]}

References

The Merck Index, 12th Edition. 4247

[1]

Search

Flutrimazole

Mechanism of action

See also

References