Talk:Gene structure
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This article was very well written. The topics and the content were relatively relevant to the topic. The only issues with this topic were that there were quite a few spelling errors. For example "Organisation" was spelled wrong. It should be spelled as "Organization." (Yp2h (talk) 01:00, 15 September 2018 (UTC)Yamini Patel)[reply]
I'd like to start a discussion on the definition of a gene. Many textbooks define a gene as a DNA sequence that's transcribed to produce a functional RNA. This means that there are two types of genes: protein-coding genes and noncoding genes. It also means that the gene is just the DNA that's found between the transcription start site and the transcription termination site. Thus, regulatory sequences are defined as elements that control the expression of genes but they are not part of genes.
I've been discussing this issue on my blog for many years ....
What Is a Gene?https://sandwalk.blogspot.com/2007/01/what-is-gene.html
and Kostas Kampourakis has written a whole book about it (Kampourakis, K. (2017). Making Sense of Genes. Cambridge Univesity Press. Cambridge, UK). He defines a gene as ...
I think we should adopt this definition, one that doesn't include regulatory sequences.
I also think we need to address some of the misinformation that's out there. For example. reference #2 (Polyak and Meyerson, 2003) says,
That statement if flawed for several reasons but it reflects a common (mistaken) view that needs to be discussed in this article. Genome42 (talk) 23:01, 1 June 2022 (UTC)[reply]
Continued at talk:gene#Defining "gene" and talk:gene#Definition of "gene" (again) - T.Shafee(Evo&Evo)talk 04:04, 2 March 2023 (UTC)[reply]