Sulfiram (INN) or monosulfiram, trade name Tetmosol, is an ectoparasiticide used in the treatment and prevention of scabies.[1] It is usually sold as a solution or medicated soap, sometimes in combination with benzyl benzoate.
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| Clinical data | |
|---|---|
| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Topical |
| ATCvet code | |
| Pharmacokinetic data | |
| Bioavailability | Very low |
| Excretion | Renal, unchanged |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.002.171 |
| Chemical and physical data | |
| Formula | C10H20N2S3 |
| Molar mass | 264.46 g·mol−1 |
Sulfiram is now rarely used, but, as of 2015[update], is still available in Brazil, India, and South Africa (as monotherapy).[1]
Adverse effects
Dizziness, headache, fatigue and erythematous rash may occur.[2] A single case of toxic epidermal necrolysis was reported in 1968.[3]
Sulfiram is structurally related to disulfiram (Antabuse), and readily converts to disulfiram when exposed to light. Like disulfiram, it can produce an unpleasant reaction when consumed with alcohol.[1][4]
References
External links
- Tetmosol* soap – South African Electronic Package Insert