Large neutral amino acids transporter small subunit 1

Large neutral amino acids transporter small subunit 1, also known as 4F2 light chain, or CD98 light chain is a protein that in humans is encoded by the SLC7A5 gene.^[5][6]

SLC7A5
Identifiers
Aliases	SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1, solute carrier family 7 member 5
External IDs	OMIM: 600182; MGI: 1298205; HomoloGene: 55759; GeneCards: SLC7A5; OMA:SLC7A5 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q24.2 Start 87,830,023 bp[1] End 87,869,507 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8 E1|8 Start 122,607,889 bp[2] End 122,634,433 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium beta cell dorsal motor nucleus of vagus nerve mucosa of pharynx inferior olivary nucleus mucosa of esophagus body of tongue corpus epididymis left testis right testis Top expressed in lacrimal gland fetal liver hematopoietic progenitor cell lens seminal vesicula spermatocyte calvaria optic nerve parotid gland seminiferous tubule blood More reference expression data BioGPS n/a
Gene ontology Molecular function peptide antigen binding L-amino acid transmembrane transporter activity amino acid transmembrane transporter activity neutral amino acid transmembrane transporter activity antiporter activity protein binding transmembrane transporter activity Cellular component integral component of membrane membrane intracellular membrane-bounded organelle plasma membrane apical plasma membrane extracellular exosome integral component of plasma membrane cytoplasm cytosol Biological process amino acid transmembrane transport cell differentiation cellular amino acid metabolic process nervous system development multicellular organism development L-amino acid transport neutral amino acid transport leukocyte migration amino acid transport L-alpha-amino acid transmembrane transport transport transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8140 20539 Ensembl ENSG00000103257 ENSMUSG00000040010 UniProt Q01650 Q9Z127 RefSeq (mRNA) NM_003486 NM_011404 RefSeq (protein) NP_003477 NP_035534 Location (UCSC) Chr 16: 87.83 – 87.87 Mb Chr 8: 122.61 – 122.63 Mb PubMed search [3] [4]
Wikidata
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