Sodium-coupled neutral amino acid transporter 3

Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene.^[5][6][7]

SLC38A3
Identifiers
Aliases	SLC38A3, G17, NAT1, SN1, SNAT3, solute carrier family 38 member 3
External IDs	OMIM: 604437; MGI: 1923507; HomoloGene: 4983; GeneCards: SLC38A3; OMA:SLC38A3 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p21.31 Start 50,205,246 bp[1] End 50,221,486 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9 F1|9 58.69 cM Start 107,527,833 bp[2] End 107,546,729 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver muscle of thigh body of pancreas C1 segment ganglionic eminence right frontal lobe ventricular zone gastrocnemius muscle caudate nucleus amygdala Top expressed in neural layer of retina left lobe of liver Epithelium of choroid plexus muscle of thigh soleus muscle lumbar subsegment of spinal cord right ventricle superior frontal gyrus primary visual cortex ankle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function L-glutamine transmembrane transporter activity L-histidine transmembrane transporter activity L-asparagine transmembrane transporter activity L-alanine transmembrane transporter activity antiporter activity symporter activity amino acid transmembrane transporter activity Cellular component integral component of membrane membrane plasma membrane integral component of plasma membrane basolateral plasma membrane Biological process L-alanine transport sodium ion transport histidine transport female pregnancy positive regulation of transcription from RNA polymerase II promoter in response to acidic pH positive regulation of glutamine transport brain development asparagine transport amino acid transport cellular response to potassium ion starvation glutamine transport ion transport amino acid transmembrane transport transmembrane transport L-histidine transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10991 76257 Ensembl ENSG00000188338 ENSMUSG00000010064 UniProt Q99624 Q9DCP2 RefSeq (mRNA) NM_006841 NM_001199217 NM_001199218 NM_023805 RefSeq (protein) NP_006832 NP_001186146 NP_001186147 NP_076294 Location (UCSC) Chr 3: 50.21 – 50.22 Mb Chr 9: 107.53 – 107.55 Mb PubMed search [3] [4]
Wikidata
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