SKF-38,393

SKF-38,393
Identifiers
	IUPAC name 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;
CAS Number	67287-49-4;
PubChem CID	1242;
IUPHAR/BPS	935;
ChemSpider	1205;
UNII	R7TF327S2C;
ChEBI	CHEBI:131793 ;
ChEMBL	ChEMBL24077 ;
CompTox Dashboard (EPA)	DTXSID10894836 ;
Chemical and physical data
Formula	C16H17NO2
Molar mass	255.317 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3;

SKF-38393 is a synthetic compound of the benzazepine chemical class which acts as a selective D₁/D₅ receptor partial agonist.^[1] It has stimulant and anorectic effects.^[2]^[3]

The trimethylation of SKF-38,393 leads to a named agent called Trepipam.

As with fenoldopam the inclusion of a chlorine halogen gave an agent that is called SKF-81,297.

References

Identifiers

IUPAC name 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
CAS Number	67287-49-4
PubChem CID	1242
IUPHAR/BPS	935
ChemSpider	1205
UNII	R7TF327S2C
ChEBI	CHEBI:131793^Y
ChEMBL	ChEMBL24077^Y
CompTox Dashboard (EPA)	DTXSID10894836
Chemical and physical data
Formula	C₁₆H₁₇NO₂
Molar mass	255.317 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3