Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).[5]
Function
This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation.[5] It has also been shown to interact with Nogo-A (RTN4), an neurite outgrowth inhibitor.[6] S1PR2 is expressed in neuronal and vascular cells and is crucial for the migration and growth of developing and injured neuronal and vascular system.[7] [8]
Evolution
See also
References
Further reading
External links
- "Lysophospholipid Receptors: S1P2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-05.
- Lysophospholipid+receptors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.