Ro01-6128

Ro01-6128
Identifiers
	IUPAC name ethyl diphenylacetylcarbamate;
PubChem CID	9903898;
IUPHAR/BPS	1386;
ChemSpider	8079552;
CompTox Dashboard (EPA)	DTXSID701028585 ;
Chemical and physical data
Formula	C17H17NO3
Molar mass	283.327 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c2ccccc2C(C(=O)NC(=O)OCC)c1ccccc1;
	InChI InChI=1S/C17H17NO3/c1-2-21-17(20)18-16(19)15(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19,20); Key:ILSZPWZFQHSKLW-UHFFFAOYSA-N;
	(verify)

Ro01-6128 is a drug used in scientific research, which acts as a selective positive allosteric modulator for the metabotropic glutamate receptor subtype mGluR₁.^[1]^[2]^[3] It was derived by modification of a lead compound found via high-throughput screening, and was further developed to give the improved compound Ro67-4853.^[4]

References

Identifiers

IUPAC name ethyl diphenylacetylcarbamate
PubChem CID	9903898
IUPHAR/BPS	1386
ChemSpider	8079552
CompTox Dashboard (EPA)	DTXSID701028585
Chemical and physical data
Formula	C₁₇H₁₇NO₃
Molar mass	283.327 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c2ccccc2C(C(=O)NC(=O)OCC)c1ccccc1
InChI InChI=1S/C17H17NO3/c1-2-21-17(20)18-16(19)15(13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,15H,2H2,1H3,(H,18,19,20) Key:ILSZPWZFQHSKLW-UHFFFAOYSA-N
(verify)