Río Blanco (Spanish for "White River") may refer to:
Argentina
Belize
- Rio Blanco (Belize)
Bolivia
- Río Blanco (Bolivia), a tributary of the Rio Guaporé
Chile
- Río Blanco (Aconcagua)
- Río Blanco (Ajatama)
- Río Blanco (Loa)
- Río Blanco (Chollay)
Guatemala
Mexico
- Río Blanco, Chiapas
- Río Blanco, Oaxaca
- Río Blanco, Veracruz, a town in Veracruz state
- Río Blanco (Veracruz), a river in Veracruz state
Nicaragua
Peru
- Rio Blanco mine, a copper mine in Loreto Region
- Río Blanco or Yuraqmayu, a river in the Lima Region, Peru
Puerto Rico
- Río Blanco (Ponce, Puerto Rico), a tributary of the Río Prieto
Spain
- Río Blanco, Granada, a river in Sierra de Cogollos
United States
- Rio Blanco (Colorado), a tributary of the San Juan River
- Rio Blanco County, Colorado
- Rio Blanco Oil Shale Company
- Blanco River (Texas), a tributary of the San Marcos River
Uruguay
- what would be the native (Spanish) name of the city of Río Branco, Uruguay, actually named in Portuguese in honor of a Brazilian diplomat