Panagiotis Markopoulos (Greek: Παναγιώτης Μαρκόπουλος) (1916–1996) was a Greek politician. He was three times Minister of the Interior of Greece (1984, 1985, 1989). He was acting minister of public order (1989).
| Preceded by | Minister of the Interior of Greece 1984 | Succeeded by Menios Koutsogiorgas |
| Preceded by Menios Koutsogiorgas | Minister of the Interior of Greece 1985 | Succeeded by Menios Koutsogiorgas |
| Preceded by | Minister of the Interior of Greece 1989 | Succeeded by |
| Preceded by | Minister of Public Order of Greece 1989 (acting) | Succeeded by |