PYGO2

Pygopus homolog 2 is a protein that in humans is encoded by the PYGO2 gene.^[5][6]

PYGO2
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2XB1, 4UP0, 4UP5
Identifiers
Aliases	PYGO2, 1190004M21Rik, pygopus family PHD finger 2
External IDs	OMIM: 606903; MGI: 1916161; HomoloGene: 44519; GeneCards: PYGO2; OMA:PYGO2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.3 Start 154,957,026 bp[1] End 154,963,853 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F1 Start 89,337,521 bp[2] End 89,342,435 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of arm cardiac muscle tissue of right atrium myocardium of left ventricle nasal epithelium cardia right adrenal gland anterior pituitary right adrenal cortex granulocyte oocyte Top expressed in papillary dermis yolk sac granulocyte dermal papilla cumulus cell gastrula ventricular zone lens epiblast lip More reference expression data BioGPS n/a
Gene ontology Molecular function histone binding metal ion binding protein binding chromatin binding histone acetyltransferase regulator activity Cellular component nucleoplasm nucleus beta-catenin-TCF complex Biological process roof of mouth development regulation of histone H3-K4 methylation in utero embryonic development regulation of mammary gland epithelial cell proliferation positive regulation of chromatin binding mammary gland development brain development lens development in camera-type eye developmental growth regulation of histone acetylation spermatid development canonical Wnt signaling pathway beta-catenin-TCF complex assembly kidney development spermatid nucleus differentiation post-embryonic development Wnt signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 90780 68911 Ensembl ENSG00000163348 ENSMUSG00000047824 UniProt Q9BRQ0 n/a RefSeq (mRNA) NM_138300 NM_001293763 NM_001293766 NM_001293767 NM_001293768 NM_026869 RefSeq (protein) NP_612157 n/a Location (UCSC) Chr 1: 154.96 – 154.96 Mb Chr 3: 89.34 – 89.34 Mb PubMed search [3] [4]
Wikidata
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