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Protein-coding gene in the species Homo sapiens
DNA primase large subunit is an enzyme that in humans is encoded by the PRIM2 gene.[5][6]
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit.[6]
References
Further reading
External links
- PDBe-KB provides an overview of all the structure information available in the PDB for Human DNA primase large subunit (PRIM2)