POLD4

DNA polymerase delta subunit 4, also known as DNA polymerase delta subunit p12, is a protein that in humans is encoded by the POLD4 gene.^[5] It is a component of the DNA polymerase delta complex.

POLD4
Identifiers
Aliases	POLD4, POLDS, p12, polymerase (DNA) delta 4, accessory subunit, DNA polymerase delta 4, accessory subunit
External IDs	OMIM: 611525; MGI: 1916995; HomoloGene: 10909; GeneCards: POLD4; OMA:POLD4 - orthologs
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q13.2 Start 67,350,772 bp[1] End 67,356,972 bp[1]
Gene location (Mouse) Chr. Chromosome 19 (mouse)[2] Band 19|19 A Start 4,281,953 bp[2] End 4,283,688 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon right lobe of liver granulocyte duodenum appendix lymph node Descending thoracic aorta blood left coronary artery right coronary artery Top expressed in spleen white adipose tissue urinary bladder granulocyte adrenal gland bone marrow pancreas islet of Langerhans lip muscle of thigh More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding DNA-directed DNA polymerase activity Cellular component delta DNA polymerase complex nucleoplasm nucleolus mitochondrion cytosol nucleus Biological process DNA-dependent DNA replication nucleotide-excision repair, DNA gap filling DNA synthesis involved in DNA repair translesion synthesis transcription-coupled nucleotide-excision repair nucleotide-excision repair, DNA incision telomere maintenance nucleotide-excision repair, DNA incision, 5'-to lesion DNA repair cellular response to DNA damage stimulus telomere maintenance via semi-conservative replication DNA replication DNA mismatch repair Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57804 69745 Ensembl ENSG00000175482 ENSMUSG00000024854 UniProt Q9HCU8 Q9CWP8 RefSeq (mRNA) NM_001256870 NM_021173 NM_027196 RefSeq (protein) NP_001243799 NP_066996 NP_081472 Location (UCSC) Chr 11: 67.35 – 67.36 Mb Chr 19: 4.28 – 4.28 Mb PubMed search [3] [4]
Wikidata
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