Route 338, or Highway 338, may refer to:
Australia
Canada
- Manitoba Provincial Road 338
- Prince Edward Island Route 338
Quebec Route 338
Hungary
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Japan
Thailand
United States
Georgia State Route 338
Kentucky Route 338
Maryland Route 338 (former)
Nevada State Route 338
New Mexico State Road 338- New York:
Ohio State Route 338 (former)- Ohio State Route 338J (former)
Pennsylvania Route 338
Puerto Rico Highway 338
Tennessee State Route 338- Texas:
Virginia State Route 338
Wyoming Highway 338
| Preceded by 337 | Lists of highways 338 | Succeeded by 339 |