LCOR

LCOR
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2COB
Identifiers
Aliases	LCOR, MLR2, ligand dependent nuclear receptor corepressor, C10orf12
External IDs	OMIM: 607698; MGI: 2443930; HomoloGene: 22914; GeneCards: LCOR; OMA:LCOR - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	96,995,956 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	41,574,975 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; jejunal mucosa; ; mucosa of paranasal sinus; ; mucosa of ileum; ; visceral pleura; ; cardia; ; pylorus; ; renal medulla; ; nipple; ; mucosa of sigmoid colon;
	Top expressed in
	epithelium of stomach; ; ventromedial nucleus; ; migratory enteric neural crest cell; ; Rostral migratory stream; ; ciliary body; ; lateral septal nucleus; ; mammillary body; ; human fetus; ; retinal pigment epithelium; ; left colon;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; transcription factor binding;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	84458
	212391
	ENSG00000196233
	ENSMUSG00000025019
	Q96JN0
	Q6ZPI3
	NM_001170765; NM_001170766; NM_001346516; NM_015652; NM_032440
	NM_172154; NM_001370767
	NP_001164236; NP_001164237; NP_001333445; NP_115816
	NP_742166; NP_001357696
	Wikidata
View/Edit Human	View/Edit Mouse

Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.^[5]^[6]^[7]

Function

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.^[7]

References

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Ligand-dependent corepressor

[5]

[6]

[7]

[1]

[2]

[3]

[4]

Search

LCOR

Contents

Function

References

Further reading

External links