Jonathan S. Weissman is the Landon T. Clay Professor of Biology at the Massachusetts Institute of Technology, a member of the Whitehead Institute, and a Howard Hughes Medical Institute Investigator. From 1996 to 2020, he was a faculty member in the department of cellular molecular pharmacology at the University of California, San Francisco.
Jonathan S. Weissman | |
|---|---|
| Nationality | American |
| Alma mater | Harvard University, MIT, Yale University |
| Known for | Ribosome profilingProtein folding |
| Awards |
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| Scientific career | |
| Fields | BiochemistryBiophysics |
| Institutions | MITHHMI |
| Doctoral advisor | Peter Kim |
| Other academic advisors | Arthur Horwich |
Education
He earned his B.A. in physics from Harvard College (1988) and his Ph.D. in physics (1993) from MIT working with Peter Kim. There, he started his studies on protein folding examining Bovine pancreatic trypsin inhibitor (BPTI).[1]
He was a postdoctoral fellow at Yale University (1993–1996), where he worked with Arthur Horwich studying the mechanism of GroEL.[2][3]
Career
Weissman's research team studies how cells ensure that proteins fold into their correct shape, as well as the role of protein misfolding in disease and normal physiology. The team also develops experimental and analytical approaches for exploring the organizational principles of biological systems and globally monitoring protein translation through ribosome profiling. A broad goal of his work is to bridge large-scale approaches and in depth mechanistic investigations to reveal the information encoded within genomes.[4][5][6]
Weissman has been a member of the National Academy of Sciences since 2009. in 2015, he co-founded the Innovative Genomics Institute with Jennifer Doudna.