Immunoconjugates are antibodies conjugated (joined) to a second molecule, usually a toxin, radioisotope or label.[1]
These conjugates are used in immunotherapy[citation needed] and to develop monoclonal antibody therapy as a targeted form of chemotherapy[2] when they are often known as antibody-drug conjugates.
When the conjugates include a radioisotope see radioimmunotherapy.When the conjugates include a toxin see immunotoxin.
References
Further reading
- Technology Insight: cytotoxic drug immunoconjugates for cancer therapy. 2007 looks useful from the abstract.
- Targeted Therapy of Cancer: New Prospects for Antibodies and Immunoconjugates. 2006 full article, 18 pages.
- Arming antibodies: prospects and challenges for immunoconjugates. 2005 10 pages.