CLC-5_Mutations.jpg (302 × 330 pixels, file size: 21 KB, MIME type: image/jpeg)
Summary
Description | Three-dimensional homology model of human CLC-5 based on the structure of ClC-ec1 (7) showing the locations of each mutated residue. Mutations are color coded according to their class; class 1 (red), class 2 (blue), and class 3 (green) and are shown with side chains in space fill. Views of the CLC-5 dimer observed from the side (A) demonstrate the location of all mutations near the subunit interface. Views from the extracellular face (B) and of the subunit interface (C) demonstrate a clear distinction in the distributions of each class of mutations. Only a single subunit is shown in B and C for clarity. |
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Author or copyright owner | American Journal of Physiology |
Source (WP:NFCC#4) | http://ajprenal.physiology.org/content/296/2/F390/F6.expansion |
Date of publication | n/a |
Use in article (WP:NFCC#7) | Dent's disease |
Purpose of use in article (WP:NFCC#8) | The mutation of the CLC-5 gene responsible for Dent's Disease |
Not replaceable with free media because (WP:NFCC#1) | n.a. |
Minimal use (WP:NFCC#3) | The article is not reproducing the entire power point teaching slide of this topic, rather the model of the genetic mutation is being used in the article for educational purposes. |
Respect for commercial opportunities (WP:NFCC#2) | n.a. |
Fair useFair use of copyrighted material in the context of Dent's disease//en.wikipedia.org/wiki/File:CLC-5_Mutations.jpgtrue |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 13:51, 7 January 2017 | ![]() | 302 × 330 (21 KB) | DatBot (talk | contribs) | Reduce size of non-free image (BOT - disable) |
15:46, 13 July 2012 | No thumbnail | 1,168 × 1,280 (256 KB) | Virgil Vaduva (talk | contribs) | Uploading an excerpt from a non-free work using File Upload Wizard |
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