FKBP10

FKBP10
Identifiers
Aliases	FKBP10, FKBP65, OI11, OI6, PPIASE, hFKBP65, BRKS1, FK506 binding protein 10, FKBP prolyl isomerase 10
External IDs	OMIM: 607063; MGI: 104769; HomoloGene: 7718; GeneCards: FKBP10; OMA:FKBP10 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,823,213 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,315,650 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; ascending aorta; ; Descending thoracic aorta; ; anterior pituitary; ; right coronary artery; ; right ovary; ; canal of the cervix; ; body of uterus; ; left ovary; ; left coronary artery;
	Top expressed in
	calvaria; ; internal carotid artery; ; external carotid artery; ; body of femur; ; fossa; ; molar; ; vas deferens; ; vestibular sensory epithelium; ; stroma of bone marrow; ; dermis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; metal ion binding; FK506 binding;
Cellular component	endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm; nucleolus;
Biological process	chaperone-mediated protein folding; histone peptidyl-prolyl isomerization; peptidyl-proline modification; protein peptidyl-prolyl isomerization;
	Sources:Amigo / QuickGO
Orthologs
	60681
	14230
	ENSG00000141756
	ENSMUSG00000001555
	Q96AY3
	Q61576
	NM_021939
	NM_001163481; NM_010221
	NP_068758
	NP_001156953; NP_034351
	Wikidata
View/Edit Human	View/Edit Mouse

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.^[5]^[6]^[7]

The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase family. It is located in endoplasmic reticulum and acts as molecular chaperones. Two alternatively spliced variants, which encode different isoform, are reported.^[7]

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