Endrisone

Endrisone
Clinical data
Trade names	Aldrisone
Other names	Delta-medrysone; 6α-Methyl-11β-hydroxypregna-1,4-diene-3,20-dione; 6α-Methyl-11β-hydroxy-Δ1-progesterone
Routes of; administration	Topical, ophthalmic
Identifiers
	IUPAC name (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one;
CAS Number	35100-44-8;
PubChem CID	71422;
ChemSpider	64512;
UNII	1QZ096EIEF;
KEGG	D03995;
ChEMBL	ChEMBL2104631;
CompTox Dashboard (EPA)	DTXSID401043364 ;
ECHA InfoCard	100.047.587
Chemical and physical data
Formula	C22H30O3
Molar mass	342.479 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@@H]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)C(=O)C;
	InChI InChI=1S/C22H30O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h7-8,10,12,15-17,19-20,25H,5-6,9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1; Key:VDNZZIYSCXESNI-ILSZZQPISA-N;

Endrisone (INN) (brand name Aldrisone), or endrysone (USAN), is a synthetic, steroidal glucocorticoid which is or has been marketed in Italy by SIFI.^[1]^[2]^[3] It is used as a topical and ophthalmic anti-inflammatory drug in the treatment of skin and eye conditions, respectively.^[1]^[2]

References