ESD (gene)

S-formylglutathione hydrolase is an enzyme that in humans is encoded by the ESD gene.^[4]

ESD
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 3FCX
Identifiers
Aliases	ESD, FGH, esterase D
External IDs	OMIM: 133280; MGI: 3781082; HomoloGene: 55623; GeneCards: ESD; OMA:ESD - orthologs
Gene location (Human) Chr. Chromosome 13 (human)[1] Band 13q14.2 Start 46,771,256 bp[1] End 46,797,420 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in popliteal artery tibial arteries Descending thoracic aorta hair follicle germinal epithelium right coronary artery Epithelium of choroid plexus optic nerve ganglionic eminence retinal pigment epithelium n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function S-formylglutathione hydrolase activity methylumbelliferyl-acetate deacetylase activity carboxylic ester hydrolase activity protein binding hydrolase activity hydrolase activity, acting on ester bonds identical protein binding Cellular component cytoplasm extracellular exosome endoplasmic reticulum lumen cytoplasmic vesicle cytosol Biological process formaldehyde catabolic process glutathione derivative biosynthetic process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2098 100040682 Ensembl ENSG00000139684 n/a UniProt P10768 n/a RefSeq (mRNA) NM_001984 XM_036158963 RefSeq (protein) NP_001975 n/a Location (UCSC) Chr 13: 46.77 – 46.8 Mb n/a PubMed search [2] [3]
Wikidata
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