Dihydrofluoxymesterone

Dihydrofluoxymesterone
Clinical data
Other names	U-7265; 5α-Dihydrofluoxymesterone; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-dihydrotestosterone; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-DHT; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-androstan-17β-ol-3-one
Routes of; administration	By mouth
Drug class	Androgen; Anabolic steroid
Chemical and physical data
Formula	C20H30FO3
Molar mass	337.455 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2CC(=O)CC[C@]12C;
	InChI InChI=1S/C20H30FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h12,14-15,23-24H,4-11H2,1-3H3/t12-,14-,15-,17-,18-,19-,20-/m0/s1; Key:PQQVQMWIMDIHJU-VIIFRJDQSA-N;

Dihydrofluoxymesterone (developmental code name U-7265) is an androgen and anabolic steroid (AAS) which was never marketed.^[1]^[2]^[3] It was assessed in the treatment of breast cancer in women in at least one clinical study in the 1970s and showed effectiveness similar to that of other AAS.^[1]^[2] The drug is the 5α-reduced analogue and metabolite of fluoxymesterone.^[1]^[2]^[3]

References

Clinical data

Other names	U-7265; 5α-Dihydrofluoxymesterone; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-dihydrotestosterone; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-DHT; 9α-Fluoro-11β-hydroxy-17α-methyl-5α-androstan-17β-ol-3-one
Routes of administration	By mouth
Drug class	Androgen; Anabolic steroid
Chemical and physical data
Formula	C₂₀H₃₀FO₃
Molar mass	337.455 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2CC(=O)CC[C@]12C
InChI InChI=1S/C20H30FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h12,14-15,23-24H,4-11H2,1-3H3/t12-,14-,15-,17-,18-,19-,20-/m0/s1 Key:PQQVQMWIMDIHJU-VIIFRJDQSA-N