Desoxycorticosterone pivalate

Deoxycorticosterone pivalate (DOCP), also known as desoxycorticosterone trimethyl acetate (DOC-TMA or DCT) and sold under the brand names Zycortal, Percorten V, and Percorten M, is a mineralocorticoid medication and a mineralocorticoid ester.^[1][2][3][4] It is formulated as a microcrystalline aqueous suspension, is administered by intramuscular injection at regular intervals, and has a prolonged duration of action.^[5] The medication is the C21 pivalate (trimethylacetate) ester of 11-deoxycorticosterone.^[1][2]

Desoxycorticosterone pivalate

Clinical data
Trade names	Zycortal, Percorten V, Percorten M, Neocortin Depositum, Neocortodina Depositum, Neodin Depositum
Other names	DOCP; Deoxycorticosterone pivalate; Desoxycortone pivalate; Deoxycortone pivalate; Percoten pivalate; Desoxycorticosterone trimethylacetate; Desoxycorticosterone trimethyl acetate; DCT; DOC-TMA; SC-46312; 21-Hydroxypregn-4-ene-3,20-dione pivalate; 21-(2,2-Dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione
Routes of administration	Intramuscular injection
Drug class	Corticosteroid; Mineralocorticoid
ATC code	H02AA03 (WHO)
Identifiers
IUPAC name [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
CAS Number	808-48-0
PubChem CID	11876263
DrugBank	DB01134
ChemSpider	10050591
UNII	16665T4A2X
KEGG	D03699
ChEBI	CHEBI:50782
ChEMBL	ChEMBL1200592
CompTox Dashboard (EPA)	DTXSID8046036
ECHA InfoCard	100.011.242
Chemical and physical data
Formula	C26H38O4
Molar mass	414.586 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)COC(=O)C(C)(C)C)CCC4=CC(=O)CC[C@]34C
InChI InChI=1S/C26H38O4/c1-24(2,3)23(29)30-15-22(28)21-9-8-19-18-7-6-16-14-17(27)10-12-25(16,4)20(18)11-13-26(19,21)5/h14,18-21H,6-13,15H2,1-5H3/t18-,19-,20-,21+,25-,26-/m0/s1 Key:VVOIQBFMTVCINR-WWMZEODYSA-N