COPB2

COPB2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5A1U, 5A1V, 5A1W, 5A1X, 5A1Y
Identifiers
Aliases	COPB2, beta'-COP, coatomer protein complex subunit beta 2, MCPH19, COPI coat complex subunit beta 2
External IDs	OMIM: 606990; MGI: 1354962; HomoloGene: 3499; GeneCards: COPB2; OMA:COPB2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	139,389,736 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	98,470,435 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; stromal cell of endometrium; ; beta cell; ; oral cavity; ; body of pancreas; ; mucosa of sigmoid colon; ; bronchial epithelial cell; ; smooth muscle tissue; ; Achilles tendon; ; rectum;
	Top expressed in
	ascending aorta; ; aortic valve; ; lobe of prostate; ; Paneth cell; ; Rostral migratory stream; ; vas deferens; ; fossa; ; seminal vesicula; ; calvaria; ; pituitary gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural molecule activity; protein binding;
Cellular component	cytoplasm; cytosol; Golgi apparatus; membrane; Golgi membrane; COPI-coated vesicle membrane; transport vesicle; membrane coat; COPI vesicle coat; cytoplasmic vesicle; endoplasmic reticulum membrane;
Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; toxin transport; endoplasmic reticulum to Golgi vesicle-mediated transport; protein transport; intracellular protein transport; intra-Golgi vesicle-mediated transport; vesicle-mediated transport;
	Sources:Amigo / QuickGO
Orthologs
	9276
	50797
	ENSG00000184432
	ENSMUSG00000032458
	P35606
	O55029
	NM_004766
	NM_015827
	NP_004757
	NP_056642
	Wikidata
View/Edit Human	View/Edit Mouse

Coatomer subunit beta is a protein that is encoded by the COPB2 gene in humans.^[5]^[6]

Function

The Golgi coatomer complex (see MIM 601924) constitutes the coat of non-clathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM]^[6]

Interactions

COPB2 has been shown to interact with:

References

External links

Human COPB2 genome location and COPB2 gene details page in the UCSC Genome Browser.
Overview of all the structural information available in the PDB for UniProt: O55029 (Mouse Coatomer subunit beta') at the PDBe-KB.

Search

COPB2

Contents

Function

Interactions

References

External links

Further reading