ANKRD25

KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene.^[5][6][7]

KANK2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4HBD
Identifiers
Aliases	KANK2, ANKRD25, MXRA3, SIP, PPKWH, KN motif and ankyrin repeat domains 2, NPHS16
External IDs	OMIM: 614610; MGI: 2384568; HomoloGene: 9163; GeneCards: KANK2; OMA:KANK2 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 11,164,267 bp[1] End 11,197,791 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A3 Start 21,678,080 bp[2] End 21,710,040 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein gastric mucosa urethra body of uterus right coronary artery popliteal artery tibial arteries canal of the cervix sural nerve left uterine tube Top expressed in ascending aorta interventricular septum aortic valve belly cord ciliary body sciatic nerve left lung lobe gastrula iris internal carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component cytoplasm mitochondrion Biological process negative regulation of G1/S transition of mitotic cell cycle negative regulation of programmed cell death negative regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription by RNA polymerase II negative regulation of vitamin D receptor signaling pathway regulation of transcription, DNA-templated transcription, DNA-templated negative regulation of cell population proliferation apoptotic process kidney epithelium development glomerular visceral epithelial cell migration regulation of Rho protein signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25959 235041 Ensembl ENSG00000197256 ENSMUSG00000032194 UniProt Q63ZY3 Q8BX02 RefSeq (mRNA) NM_015493 NM_001136191 NM_001329451 NM_145611 RefSeq (protein) NP_001129663 NP_001316380 NP_056308 NP_001366477 NP_001366478 NP_001366479 NP_001366480 NP_001366481 NP_001366482 NP_001366483 NP_001366484 NP_001366485 NP_001366486 NP_001366487 NP_001366488 NP_001366489 NP_001366490 NP_001366491 NP_001366492 NP_663586 Location (UCSC) Chr 19: 11.16 – 11.2 Mb Chr 9: 21.68 – 21.71 Mb PubMed search [3] [4]
Wikidata
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