ACER1

ACER1
Identifiers
Aliases	ACER1, ALKCDase1, ASAH3, alkaline ceramidase 1
External IDs	OMIM: 613491; MGI: 2181962; HomoloGene: 15853; GeneCards: ACER1; OMA:ACER1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	6,333,612 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	57,289,126 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; skin of thigh; ; vulva; ; human penis; ; nipple; ; oral cavity; ; vagina; ; lymph node; ; ectocervix;
	Top expressed in
	skin of external ear; ; lip; ; condyle; ; skin of back; ; epithelium of stomach; ; left colon; ; epidermis; ; skin of abdomen; ; Paneth cell; ; hair follicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	dihydroceramidase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; hydrolase activity; N-acylsphingosine amidohydrolase activity; ceramidase activity; metal ion binding;
Cellular component	membrane; integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum;
Biological process	cellular response to calcium ion; regulation of lipid metabolic process; cell differentiation; sphingosine biosynthetic process; sphingolipid biosynthetic process; response to alkaline pH; keratinocyte differentiation; ceramide metabolic process; epidermis development; lipid metabolism; ceramide catabolic process; sphingolipid metabolic process; regulation of water loss via skin; sebaceous gland development;
	Sources:Amigo / QuickGO
Orthologs
	125981
	171168
	ENSG00000167769
	ENSMUSG00000045019
	Q8TDN7
	Q8R4X1
	NM_133492
	NM_175731
	NP_597999
	NP_783858
	Wikidata
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