7-Methyl-α-ethyltryptamine

7-Methyl-α-ethyltryptamine
Identifiers
	IUPAC name 1-(7-methyl-1H-indol-3-yl)butan-2-amine;
CAS Number	13712-80-6 freebase ; 13518-76-8 hydrochloride salt;
PubChem CID	57469234;
ChemSpider	26286844;
UNII	7H5EU45L83;
CompTox Dashboard (EPA)	DTXSID60726754 ;
Chemical and physical data
Formula	C13H18N2
Molar mass	202.301 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCC(N)CC1=CNC2=C(C)C=CC=C21;
	InChI InChI=1S/C13H18N2/c1-3-11(14)7-10-8-15-13-9(2)5-4-6-12(10)13/h4-6,8,11,15H,3,7,14H2,1-2H3; Key:NBLFITFQOPGXLS-UHFFFAOYSA-N;

7-Methyl-α-ethyltryptamine (7-Me-αET) is a tryptamine derivative related to α-ethyltryptamine (αET). It was discovered by a team at Upjohn in the early 1960s.^[1] It has similar pharmacological effects to αET, but is both 3-4 times more potent as a serotonin releasing agent, and 10 times more potent as a monoamine oxidase inhibitor,^[2]^[3] making it potentially hazardous as this pharmacological profile is shared with drugs such as PMA and 4-MTA, which are known to be dangerous in humans when used at high doses.

References

[1]

[2]

[3]

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7-Methyl-α-ethyltryptamine

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References

Identifiers

IUPAC name 1-(7-methyl-1H-indol-3-yl)butan-2-amine
CAS Number	13712-80-6 freebase 13518-76-8 hydrochloride salt
PubChem CID	57469234
ChemSpider	26286844
UNII	7H5EU45L83
CompTox Dashboard (EPA)	DTXSID60726754
Chemical and physical data
Formula	C₁₃H₁₈N₂
Molar mass	202.301 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCC(N)CC1=CNC2=C(C)C=CC=C21
InChI InChI=1S/C13H18N2/c1-3-11(14)7-10-8-15-13-9(2)5-4-6-12(10)13/h4-6,8,11,15H,3,7,14H2,1-2H3 Key:NBLFITFQOPGXLS-UHFFFAOYSA-N