The 2001 CAF Cup was the 10th edition of the CAF Cup, the African continental club competition for runners up of the respective domestic leagues. It was won by Algerian team JS Kabylie who beat Étoile Sportive du Sahel of Tunisia on the away goals rule in the final, after the two teams finished level on aggregate 2-2. It was the second year in a row that JS Kabylie's won the competition after also winning the 2000 edition.
| Tournament details | |
|---|---|
| Dates | 31 March 2001 – 23 November 2001 |
| Teams | 27 |
| Final positions | |
| Champions |  JS Kabylie (2nd title) |
| Runners-up |  Étoile du Sahel |
| Tournament statistics | |
| Matches played | 48 |
First round
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
Manchester SC  | 2-4 |  ASA | 1-0 | 1-4 |
Almahalla Tripoli  | 2-3 |  ASC Ndiambour | 2-1 | 0-2 |
| MO Constantine | 3-1 |  Al-Merreikh Al-Thagher | 1-0 | 2-1 |
Katsina United  | w/o1 |  Simba FC | — | — |
Ajax Cape Town  | 3-1 |  Kampala City Council | 2-0 | 1-1 |
SM Sanga Balende  | w/o2 |  Deportivo Mongomo | 3-01 | — |
FC Jirama Antsirabe  | 2-6 |  Ferroviário | 0-3 | 2-3 |
Zanaco F.C.  | 1-1 (a) |  Green Mamba FC | 1-1 | 0-0 |
Mtibwa Sugar FC  | 2-2 (a) |  Mebrat Hail | 2-1 | 0-1 |
Oserian Fastac  | 5-2 |  Arabica FC Kirundo | 2-1 | 3-1 |
FC 105 Libreville  | 3-4 |  Cotonsport Garoua | 3-2 | 0-2 |
1 Simba FC withdrew before first leg
2 First leg abandoned with the score 3-0 due to poor visibility. CAF disqualified Mongomo for arriving late and delaying kick-off.
Five teams received a bye : JS Kabylie (Algeria), Goldfields (Ghana), Africa Sport (Ivory Coast), Wydad Casablanca (Morocco), Étoile du Sahel (Tunisia)
Second round
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
Goldfields  | 3-2 | ASA | 1-0 | 2-2 |
Wydad AC  | 3-1 | ASC Ndiambour | 1-1 | 2-0 |
| MO Constantine | 1-1 (p) |  Africa Sport | 1-0 | 0-1 |
| Katsina United | w/o1 | Ajax Cape Town | 2-2 | — |
| Cotonsport Garoua | 4-2 | SM Sanga Balende | 2-0 | 2-2 |
| Ferroviário | 4-0 | Green Mamba FC | 2-0 | 2-0 |
| JS Kabylie | 2-1 | Mebrat Hail | 2-0 | 0-1 |
| Étoile du Sahel | (a) 4-4 | Oserian Fastac | 2-0 | 2-4 |
1 Katsina United did not show up for second leg
Quarter-finals
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Étoile du Sahel | 3-0 | Ajax Cape Town | 2-0 | 1-0 |
| Ferroviário | 2-3 | Cotonsport Garoua | 2-2 | 0-1 |
| Goldfields | 0-2 | Africa Sport | 0-0 | 0-2 |
| Wydad AC | 0-3 | JS Kabylie | 0-1 | 0-2 |
Semi-finals
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Étoile du Sahel | 3-2 | Cotonsport Garoua | 3-1 | 0-1 |
| Africa Sport | 3-3 (a) | JS Kabylie | 3-1 | 0-2 |
| Étoile du Sahel | 3 – 1 | Cotonsport Garoua |
|---|---|---|
Ghodhbane  26', 93'Keïta 62' | Soussia 11' |
| Cotonsport Garoua | 1 – 0 | Étoile du Sahel |
|---|---|---|
| Wadale 32' |
Étoile du Sahel won 3–1 on aggregate and advanced to the final.
| Africa Sport | 3 – 1 | JS Kabylie |
|---|---|---|
| Nkowa 15' Dao 26'Kenmogne 53' | Report | Bezzaz 20' |
3-3 on aggregate, JS Kabylie won on away goals rule and advanced to the final.
Finals
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Étoile du Sahel | 2-2 (a) | JS Kabylie | 2-1 | 0-1 |
First leg
| Étoile du Sahel | 2 – 1 | JS Kabylie |
|---|---|---|
| Keïta 14', 73' | Report | Boubrit 42' |
Second leg
| JS Kabylie | 1 – 0 | Étoile du Sahel |
|---|---|---|
| Zafour 28' | Report |
2–2 on aggregate, JS Kabylie won on away goals rule
Champions
| 2001 CAF Cup Winners |
|---|
 |
| JS Kabylie Second Title |