The Derby North by-election was held on 17 April 1962 after the death of the incumbent Labour MP, Clifford Wilcock. It was won by the Labour candidate Niall MacDermot.
| Party | Candidate | Votes | % | ±% | |
|---|---|---|---|---|---|
| Labour | Niall MacDermot | 16,497 | 49.4 | −3.4 | |
| Liberal | Lyndon Irving | 8,479 | 25.4 | new | |
| Conservative | T.M. Wray | 7,502 | 22.5 | −24.7 | |
| Independent | T. Lynch | 886 | 2.7 | new | |
| Majority | 8,018 | 24.0 | +18.4 | ||
| Turnout | 33,364 | ||||
| Labour hold | Swing | ||||