UTP20

UTP20
Identifikatori
Aliasi	UTP20
Vanjski ID-jevi	OMIM: 612822 MGI: 1917933 HomoloGene: 38373 GeneCards: UTP20
Lokacija gena (čovjek)
Hrom.	Hromosom 12 (čovjek)
Kraj	101,386,618 bp
Lokacija gena (miš)
Hrom.	Hromosom 10 (miš)
Kraj	88,662,666 bp
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • vezivanje sa RNK;
Ćelijska komponenta	• citoplazma; • preribosome, small subunit precursor; • small-subunit processome; • Jedarce; • jedro; • 90S preribosome; • nukleoplazma; • ćelijska membrana;
Biološki proces	• endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • negative regulation of cell population proliferation; • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); • rRNA processing;
	Izvori:Amigo / QuickGO
Ortolozi
	27340
	70683
	ENSG00000120800
	ENSMUSG00000004356
	O75691
	Q5XG71
	NM_014503
	NM_175158
	NP_055318
	NP_780367
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Homolog male podjedinice procesomne komponente 20 je protein koji je kod ljudi kodiran genom UTP20.^[5]^[6]^[7]^[8]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 2.785 aminokiselina, a molekulska težina 318.385 Da.^[9]

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin

10	20	30	40	50
MKTKPVSHKT	ENTYRFLTFA	ERLGNVNIDI	IHRIDRTASY	EEEVETYFFE
GLLKWRELNL	TEHFGKFYKE	VIDKCQSFNQ	LVYHQNEIVQ	SLKTHLQVKN
SFAYQPLLDL	VVQLARDLQM	DFYPHFPEFF	LTITSILETQ	DTELLEWAFT
SLSYLYKYLW	RLMVKDMSSI	YSMYSTLLAH	KKLHIRNFAA	ESFTFLMRKV
SDKNALFNLM	FLDLDKHPEK	VEGVGQLLFE	MCKGVRNMFH	SCTGQAVKLI
LRKLGPVTET	ETQLPWMLIG	ETLKNMVKST	VSYISKEHFG	TFFECLQESL
LDLHTKVTKT	NCCESSEQIK	RLLETYLILV	KHGSGTKIPT	PADVCKVLSQ
TLQVASLSTS	CWETLLDVIS	ALILGENVSL	PETLIKETIE	KIFESRFEKR
LIFSFSEVMF	AMKQFEQLFL	PSFLSYIVNC	FLIDDAVVKD	EALAILAKLI
LNKAAPPTAG	SMAIEKYPLV	FSPQMVGFYI	KQKKTRSKGR	NEQFPVLDHL
LSIIKLPPNK	DTTYLSQSWA	ALVVLPHIRP	LEKEKVIPLV	TGFIEALFMT
VDKGSFGKGN	LFVLCQAVNT	LLSLEESSEL	LHLVPVERVK	NLVLTFPLEP
SVLLLTDLYY	QRLALCGCKG	PLSQEALMEL	FPKLQANIST	GVSKIRLLTI
RILNHFDVQL	PESMEDDGLS	ERQSVFAILR	QAELVPATVN	DYREKLLHLR
KLRHDVVQTA	VPDGPLQEVP	LRYLLGMLYI	NFSALWDPVI	ELISSHAHEM
ENKQFWKVYY	EHLEKAATHA	EKELQNDMTD	EKSVGDESWE	QTQEGDVGAL
YHEQLALKTD	CQERLDHTNF	RFLLWRALTK	FPERVEPRSR	ELSPLFLRFI
NNEYYPADLQ	VAPTQDLRRK	GKGMVAEEIE	EEPAAGDDEE	LEEEAVPQDE
SSQKKKTRRA	AAKQLIAHLQ	VFSKFSNPRA	LYLESKLYEL	YLQLLLHQDQ
MVQKITLDCI	MTYKHPHVLP	YRENLQRLLE	DRSFKEEIVH	FSISEDNAVV
KTAHRADLFP	ILMRILYGRM	KNKTGSKTQG	KSASGTRMAI	VLRFLAGTQP
EEIQIFLDLL	FEPVRHFKNG	ECHSAVIQAV	EDLDLSKVLP	LGRQHGILNS
LEIVLKNISH	LISAYLPKIL	QILLCMTATV	SHILDQREKI	QLRFINPLKN
LRRLGIKMVT	DIFLDWESYQ	FRTEEIDAVF	HGAVWPQISR	LGSESQYSPT
PLLKLISIWS	RNARYFPLLA	KQKPGHPECD	ILTNVFAILS	AKNLSDATAS
IVMDIVDDLL	NLPDFEPTET	VLNLLVTGCV	YPGIAENIGE	SITIGGRLIL
PHVPAILQYL	SKTTISAEKV	KKKKNRAQVS	KELGILSKIS	KFMKDKEQSS
VLITLLLPFL	HRGNIAEDTE	VDILVTVQNL	LKHCVDPTSF	LKPIAKLFSV
IKNKLSRKLL	CTVFETLSDF	ESGLKYITDV	VKLNAFDQRH	LDDINFDVRF
ETFQTITSYI	KEMQIVDVNY	LIPVMHNCFY	NLELGDMSLS	DNASMCLMSI
IKKLAALNVT	EKDYREIIHR	SLLEKLRKGL	KSQTESIQQD	YTTILSCLIQ
TFPNQLEFKD	LVQLTHYHDP	EMDFFENMKH	IQIHRRARAL	KKLAKQLMEG
KVVLSSKSLQ	NYIMPYAMTP	IFDEKMLKHE	NITTAATEII	GAICKHLSWS
AYMYYLKHFI	HVLQTGQINQ	KLGVSLLVIV	LEAFHFDHKT	LEEQMGKIEN
EENAIEAIEL	PEPEAMELER	VDEEEKEYTC	KSLSDNGQPG	TPDPADSGGT
SAKESECITK	PVSFLPQNKE	EIERTIKNIQ	GTITGDILPR	LHKCLASTTK
REEEHKLVKS	KVVNDEEVVR	VPLAFAMVKL	MQSLPQEVME	ANLPSILLKV
CALLKNRAQE	IRDIARSTLA	KIIEDLGVHF	LLYVLKELQT	TLVRGYQVHV
LTFTVHMLLQ	GLTNKLQVGD	LDSCLDIMIE	IFNHELFGAV	AEEKEVKQIL
SKVMEARRSK	SYDSYEILGK	FVGKDQVTKL	ILPLKEILQN	TTSLKLARKV
HETLRRITVG	LIVNQEMTAE	SILLLSYGLI	SENLPLLTEK	EKNPVAPAPD
PRLPPQSCLL	LPPTPVRGGQ	KAVVSRKTNM	HIFIESGLRL	LHLSLKTSKI
KSSGECVLEM	LDPFVSLLID	CLGSMDVKVI	TGALQCLIWV	LRFPLPSIET
KAEQLTKHLF	LLLKDYAKLG	AARGQNFHLV	VNCFKCVTIL	VKKVKSYQIT
EKQLQVLLAY	AEEDIYDTSR	QATAFGLLKA	ILSRKLLVPE	IDEVMRKVSK
LAVSAQSEPA	RVQCRQVFLK	YILDYPLGDK	LRPNLEFMLA	QLNYEHETGR
ESTLEMIAYL	FDTFPQGLLH	ENCGMFFIPL	CLMTINDDSA	TCKKMASMTI
KSLLGKISLE	KKDWLFDMVT	TWFGAKKRLN	RQLAALICGL	FVESEGVDFE
KRLGTVLPVI	EKEIDPENFK	DIMEETEEKA	ADRLLFSFLT	LITKLIKECN
IIQFTKPAET	LSKIWSHVHS	HLRHPHNWVW	LTAAQIFGLL	FASCQPEELI
QKWNTKKTKK	HLPEPVAIKF	LASDLDQKMK	SISLASCHQL	HSKFLDQSLG
EQVVKNLLFA	AKVLYLLELY	CEDKQSKIKE	DLEEQEALED	GVACADEKAE
SDGEEKEEVK	EELGRPATLL	WLIQKLSRIA	KLEAAYSPRN	PLKRTCIFKF
LGAVAMDLGI	DKVKPYLPMI	IAPLFRELNS	TYSEQDPLLK	NLSQEIIELL
KKLVGLESFS	LAFASVQKQA	NEKRALRKKR	KALEFVTNPD	IAAKKKMKKH
KNKSEAKKRK	IEFLRPGYKA	KRQKSHSLKD	LAMVE

Reference

Dopunska literatura

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[8]

[1]

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